We have been involved in Cancer Research Trials since June of 1986 and we are proud that our first patient is still living today! Since 1986 we have entered 496 patients in clinical trials. We have enrolled patients in 122 different trials over 26 years.We have been involved in 8 clinical trials which lead to new FDA approvals, for drugs such as Taxol, Herceptin, and most recently Affinitor!
As a person who has been diagnosed with cancer, you should be well informed. You may have several treatment choices. It is important to learn about your options. One choice you may have is a cancer clinical trial. Your doctor may suggest this option for you.
Trials we participate in are Phase II and Phase III, no Phase 1. Examples of trials we have been involved in are: Breast, Rectal, Gastric, Leukemia, Lymphoma, Lung, Sarcoma, Carcinoid, Prostate, Renal, Ovarian, Myeloma, Melanoma, Pancreas, Brain, Hepatoma, Head and Neck, Uterine and Prostrate Prevention. We also participate in Biospecimen protocols, registries, and quality of life studies.
Is a clinical trial right for you?
All you have to do is ask!
Clinical trials are research studies that involve people. They are the final step in a long process that begins with research in a lab. Many treatments used today are the result of past clinical trials.
In cancer research, clinical trials are designed to answer questions about new ways to:
- Treat Cancer
- Find and diagnose cancer
- Prevent cancer
- Manage symptoms of cancer or its treatment
Clinical trials take place in phases. For a treatment to become part of standard treatment, it must first go through 3 or 4 clinical trial phases. You do not have to take part in all phases. the early phases make sure the treatment is safe. Later phases show if it works better than the standard treatment.
Phase I trials find safe doses, to decide how the new treatment should be given and to see how the new treatment affects the human body. Usually 13-30 people take part in a study of this nature.
Phase II trials determine if the new treatment has an effect on a certain cancer and evaluates how the new treatment affects the human body. Usually less than 100 people take part in these studies.
Phase III trials compare the new treatment (or new use of a treatment) with the current standard treatment. These trials enroll from 100 to thousands of people.
The Cancer Centers of Southwest Oklahoma only participates in Phase II and III clinical trials.
A placebo is designed to look like the medicine being tested, but it is not active. In some cases, a study may compare standard treatment plus a new treatment, to standard treatment plus a placebo. You will be told if the study uses a placebo.
Randomization is a process used in some clinical trials to prevent bias. Bias occurs when a trial’s results are affected by human choices or other factors not related to the treatment being tested.
Benefits of a Clinical Trial
Clinical trials offer high-quality cancer care. If you are in a randomized study and do not receive the new treatment being tested, you will receive the best known standard treatment. This may be as good as, or better than, the new approach.
If a new treatment is proven to work and you are taking it, you may be among the first to benefit.
You have the chance to help others and improve cancer treatment.
Standard treatment is what experts agree is the current best treatment. This treatment has been tested in past clinical trials. It is often widely used by doctors. It has been proven effective. It is also called “best practice” or “standard of care.”
Making a Decision About Your Cancer Clinical Trial
Q:What are the possible benefits of participating in a Cancer clinical trial?
Q:What are the possible risks of participating in a Cancer clinical trial?
Common Fears and Concerns
Q: Will I know all of the risks?
Q: Will I understand what it all means?
It can easily be overwhelming: the diagnosis, the information, the choices. If you feel overwhelmed about the amount or type of information you are given, ask to talk with an oncology Nurse Navigator. You may learn that the choices are not as intimidating as they seem.
Q: Will I be treated like a “guinea pig”
No. You will receive either the new treatment or the best standard treatment available. People who received treatment through a clinical trial generally find it to be a very positive experience and feel that they received good care and attention, no matter what the outcome of the disease.
Q: What if my doctor didn’t mention this option to me?
Q: What is Randomization
Q: Aren’t clinical trials a “last resort”?
Q: What is a Placebo?
BENEFITS OF A CLINICAL TRIAL:
Download PDF of Clinical Trials Information